Blooducation Blooducation

Classification and management of myelodysplasia – Dr Manoj Raghavan

Dr Manoj Raghavan speaks to Suzy about the 2016 revised WHO classification of MDS and gives some hints about what is likely to be coming in the revised BSH guideline. Dr Manoj Raghavan Classification – see link below for full definitions. Cytopenias defined as haemoglobin <100g/L, platelet count <100 x109/L, neutrophils <1.8 x109/L. These differ… Read More

Management of acute myeloid leukaemia – Dr Manos Nikolousis

This podcasts have been accredited by the Royal College of Pathologists for 1 continuing professional development (CPD) point per podcast Helen talks to Dr Manos Nikolousis about the management of acute myeloid leukaemia Dr Manos Nikolousis Learning Points: • Remember to consider fertility in work up of young patients. • ELN risk stratification – good,… Read More

Current management of multiple myeloma – Professor Guy Pratt

With so many new therapies for myeloma it can be difficult to keep up. Professor Guy Pratt speaks to Helen about recent changes to diagnosis of myeloma and emerging therapies Professor Guy Pratt Key learning points Diagnosis In addition to symptomatic disease (CRAB) + plasma cells >10% + paraprotein, multiple myeloma can also be defined… Read More

Current management of chronic lymphocytic leukaemia – Dr Helen Parry

Current management of chronic lymphocytic leukaemia Helen and Suzy Learning points Diagnosis of CLL: clonal B cell population >5 x 109/L with typical phenotype (CD5+ CD23+, 19+, 20+ FMC7-, weak/- CD79b) <5 x 199/L lymphocytes but same clonal phenotype = Monoclonal B cell Lymphocytosis (MBL) LN or extramedullary involvement but <5 x 109/L lymphocytes =… Read More

Appropriate use of O D neg blood – Dr Suzy Morton

O D negative blood is in demand, and use will always run higher than the proportion of donors, but why is it so crucial to maintain the supply and how can we make sure we are using it wisely? Helen talks to Dr Suzy Morton about the issues. Helen and Suzy O D neg donors… Read More

An update on the management of Follicular Lymphoma – Dr Toby Eyre

An update on the management of Follicular Lymphoma - Dr Toby Eyre Learning points: Follicular lymphoma is a germinal centre derived, low grade lymphoma. Most present with advanced stage disease (as per Ann Arbor)- Must identify early stage disease (1 & localised 2) as potentially curative and management differs. Biopsy: architecture and IHC inc CD10+,… Read More